TRANSDERMAL DRUG TRANSPORT AND METABOLISM .1. COMPARISON OF INVITRO AND INVIVO RESULTS

被引：37

作者：

GUZEK, DB ^{[1
]}

KENNEDY, AH ^{[1
]}

MCNEILL, SC ^{[1
]}

WAKSHULL, E ^{[1
]}

POTTS, RO ^{[1
]}

机构：

[1] PFIZER CENT RES, GROTON, CT 06340 USA

来源：

PHARMACEUTICAL RESEARCH | 1989年 / 6卷 / 01期

关键词：

D O I：

10.1023/A:1015891400924

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

收藏

页码：33 / 39

页数：7

相关论文

共 25 条

[1] BICKERS DR, 1980, CURRENT CONCEPTS CUT, P95
[2] SKIN STRUCTURE AND METABOLISM - RELEVANCE TO THE DESIGN OF CUTANEOUS THERAPEUTICS
BUCKS, DAW
[J]. PHARMACEUTICAL RESEARCH, 1984, (04) : 148 - 153
[3] GENERAL PHYSICAL MODEL FOR SIMULTANEOUS DIFFUSION AND METABOLISM IN BIOLOGICAL-MEMBRANES - COMPUTATIONAL APPROACH FOR THE STEADY-STATE CASE
FOX, JL
YU, CD
HIGUCHI, WI
HO, NFH
[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1979, 2 (01) : 41 - 57
[4] PERCUTANEOUS METABOLISM WITH SATURABLE ENZYME-KINETICS
GUY, RH
HADGRAFT, J
[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1982, 11 (03) : 187 - 197
[5] Guy RH, 1985, MODELS DERMATOLOGY, V2, P170
[6] HADGRAFT J, 1980, INT J PHARM, V4, P229, DOI 10.1016/0378-5173(80)90138-6
[7] HADGRAFT J, 1985, DESIGN PRODRUGS, P271
[8] Hoelgaard A., 1986, ADV DRUG DELIVERY SY, P111
[9] A MULTISAMPLE APPARATUS FOR KINETIC EVALUATION OF SKIN PENETRATION INVITRO - THE INFLUENCE OF VIABILITY AND METABOLIC STATUS OF THE SKIN
HOLLAND, JM
KAO, JY
WHITAKER, MJ
[J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 1984, 72 (02) : 272 - 280
[10] KAO J, 1987, J PHARMACOL EXP THER, V241, P482