NEUROTROPHIC SECOAROMADENDRANE-TYPE SESQUITERPENES FROM THE LIVERWORT PLAGIOCHILA-FRUTICOSA

被引：17

作者：

FUKUYAMA, Y

ASAKAWA, Y

机构：

[1] Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, 770, Yamashiro-cho

来源：

PHYTOCHEMISTRY | 1991年 / 30卷 / 12期

关键词：

PLAGIOCHILA-FRUTICOSA; JUNGERMANNIALES; HEPATICAE; PLAGIOCHILAL-B; PLAGIOCHILINE-A; PLAGIOCHILINE-J; AND PLAGIOCHILINE-K; PLAGIOCHILIDE; SECOAROMADENDRANE-TYPE SESQUITERPENE; NEUROTROPHIC ACTIVITY; CHOLINE ACETYLTRANSFERASE ACTIVITY;

D O I：

10.1016/0031-9422(91)83467-Y

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new sesquiterpene dialdehyde, plagiochilal B, isolated from the liverwort Plagiochila fruticosa exhibits not only acceleration of neurite sprouting but also enhancement of choline acetyltransferase activity on a neuronal cell culture of fetal rat cerebral hemisphere at 10(-5) M. Additionally, two new secoaromadendranes, plagiochilines J and K were isolated. The structures of the new secoaromadendrane-type sesquiterpenes were established by extensive 2D NMR data and chemical correlation with plagiochiline A.

引用

页码：4061 / 4065

页数：5

共 16 条

[1] PLAGIOCHILINES-C, PLAGIOCHILINES-D, PLAGIOCHILINES-E, AND PLAGIOCHILINES-F 4 NOVEL SECOAROMADENDRANE-TYPE SESQUITERPENE HEMIACETALS FROM PLAGIOCHILA-ASPLENIOIDES AND PLAGIOCHILA-SEMIDECURRENS [J].