PROTEOLYTIC PROCESSING OF HUMAN FACTOR-VIII - CORRELATION OF SPECIFIC CLEAVAGES BY THROMBIN, FACTOR XA, AND ACTIVATED PROTEIN-C WITH ACTIVATION AND INACTIVATION OF FACTOR-VIII COAGULANT ACTIVITY

被引：514

作者：

EATON, D ^{[1
]}

RODRIGUEZ, H ^{[1
]}

VEHAR, GA ^{[1
]}

机构：

[1] GENENTECH INC,DEPT PROT BIOCHEM,SAN FRANCISCO,CA 94080

来源：

关键词：

D O I：

10.1021/bi00350a035

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：505 / 512

页数：8

共 34 条

[1] BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3
[2] COAGULATION FACTOR-V AND FACTOR-VIII AND CERULOPLASMIN CONSTITUTE A FAMILY OF STRUCTURALLY RELATED PROTEINS
CHURCH, WR
JERNIGAN, RL
TOOLE, J
HEWICK, RM
KNOPF, J
KNUTSON, GJ
NESHEIM, ME
MANN, KG
FASS, DN
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (22): : 6934 - 6937
[3] DAVIE EW, 1975, PROTEASES BIOLOGICAL, V2, P65
[4] ESMON CT, 1979, J BIOL CHEM, V254, P964
[5] FASS D, 1983, THROMB HAEMOSTASIS, V50, P262
[6] FASS D, 1984, FED P FED AM SOC EXP, V43, P1976
[7] FASS DN, 1982, BLOOD, V59, P594
[8] INTERNAL DUPLICATION AND SEQUENCE HOMOLOGY IN FACTOR-V AND FACTOR-VIII
FASS, DN
HEWICK, RM
KNUTSON, GJ
NESHEIM, ME
MANN, KG
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (06) : 1688 - 1691
[9] PURIFICATION AND CHARACTERIZATION OF A HIGHLY PURIFIED HUMAN FACTOR-VIII CONSISTING OF A SINGLE TYPE OF POLYPEPTIDE-CHAIN
FAY, PJ
CHAVIN, SI
SCHROEDER, D
YOUNG, FE
MARDER, VJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (23): : 7200 - 7204
[10] FOSTER BW, 1983, J BIOL CHEM, V258, P3970