MAXIMUM RECOMMENDED DOSES OF LIGNOCAINE ARE NOT TOXIC

被引：30

作者：

PALVE, H ^{[1
]}

KIRVELA, O ^{[1
]}

OLIN, H ^{[1
]}

SYVALAHTI, E ^{[1
]}

KANTO, J ^{[1
]}

机构：

[1] TURKU UNIV HOSP,DEPT PHARMACOL,SF-20520 TURKU,FINLAND

来源：

BRITISH JOURNAL OF ANAESTHESIA | 1995年 / 74卷 / 06期

关键词：

ANESTHETICS LOCAL; LIGNOCAINE; TOXICITY; LOCAL ANESTHETICS;

D O I：

10.1093/bja/74.6.704

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

The maximum recommended doses of lignocaine are frequently exceeded in clinical practice as some blocks may need more lignocaine to produce adequate anaesthesia. We have examined the success rate of brachial plexus block, possible toxic symptoms after a dose of lignocaine 900 mg with adrenaline, and the maximum plasma concentration of lignocaine produced in 17 adult patients. In all patients, the block was excellent and no toxic symptoms were encountered. The highest mean lignocaine plasma concentration was 2.9 mu g ml(-1) 45 min after the block. We conclude that in brachial plexus block, the dose of lignocaine with adrenaline can be as high as 900 mg without fear of toxic symptoms.

引用

页码：704 / 705

页数：2

共 6 条

[1] TRANSARTERIAL BRACHIAL-PLEXUS ANESTHESIA FOR HAND SURGERY - A RETROSPECTIVE ANALYSIS OF 346 CASES [J].