SYNTHESIS AND NMR-STUDIES OF Z-ISOMERS AND E-ISOMERS OF 10-OXO AND 10-HYDROXY DERIVATIVES OF AMITRIPTYLINE AND NORTRIPTYLINE

被引：5

作者：

LASSEN, N

PERREGAARD, J

机构：

来源：

ACTA CHEMICA SCANDINAVICA SERIES B-ORGANIC CHEMISTRY AND BIOCHEMISTRY | 1983年 / 37卷 / 04期

关键词：

D O I：

10.3891/acta.chem.scand.37b-0335

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：335 / 340

页数：6

共 12 条

[1] STEREOSPECIFIC HYDROXYLATION OF NORTRIPTYLINE IN MAN IN RELATION TO INTERINDIVIDUAL DIFFERENCES IN ITS STEADY-STATE PLASMA LEVEL [J].

BERTILSSON, L ;

ALEXANDERSON, B .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1972, 4 (04) :201-+

[2] STEADY-STATE PLASMA-CONCENTRATIONS OF CIS-10-OH AND TRANS-10-OH AMITRIPTYLINE METABOLITES [J].

BOCK, JL ;

GILLER, E ;

GRAY, S ;

JATLOW, P .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1982, 31 (05) :609-616

[3] ANTIDEPRESSANTS . TETRABENAZINE-ANTAGONIZING ACTIVITY IN A SERIES OF 5H-DIBENZO[A,D]CYCLOHEPTENE-5-PROPYLAMINES [J].

ENGELHARDT, EL ;

CHRISTY, ME ;

COLTON, CD ;

FREEDMAN, MB ;

BOLAND, CC ;

HALPERN, LM ;

VERNIER, VG ;

STONE, CA .

JOURNAL OF MEDICINAL CHEMISTRY, 1968, 11 (02) :325-+

[4]

GARLAND WA, 1979, CLIN PHARMACOL THER, V25, P844

[5]

HYTTEL J, 1980, ACTA PHARMACOL TOX, V47, P53

[6]

JUST G, 1976, SYNTHESIS-STUTTGART, P457

[7] ANALOGS OF PHENOTHIAZINES .6. STEREOCHEMICAL ASSIGNMENT OF ISOMERIC AMINOALKYLIDENE DERIVATIVES OF XANTHENES AND THIOXANTHENES WITH NEUROPHARMACOLOGICAL ACTIVITY [J].

KAISER, C ;

WARREN, RJ ;

ZIRKLE, CL .

JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (01) :131-133

[8]

KOLLONITSCH J, 1966, Patent No. 3234279

[9] E-10-HYDROXYLATION AND Z-10-HYDROXYLATION OF NORTRIPTYLINE - RELATIONSHIP TO POLYMORPHIC DEBRISOQUINE HYDROXYLATION [J].

MELLSTROM, B ;

BERTILSSON, L ;

SAWE, J ;

SCHULZ, HU ;

SJOQVIST, F .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1981, 30 (02) :189-193

[10] AMITRIPTYLINE METABOLITES - SYNTHESIS OF (R,S)-(Z)- AND (R,S)-(E)- N-METHYL(10,11-DIHYDRO-10-HYDROXY-5H-DIBENZO[A,D]CYCLOHEPTENE)-DELTA-5GAMMA-PROPYLAMINE [J].

REMY, DC ;

VANSAUN, WA ;

ENGELHAR.EL .

JOURNAL OF ORGANIC CHEMISTRY, 1973, 38 (04) :700-703

← 1 2 →