PRENYL PROTEINS IN EUKARYOTIC CELLS - A NEW TYPE OF MEMBRANE ANCHOR

被引：457

作者：

GLOMSET, JA

GELB, MH

FARNSWORTH, CC

机构：

[1] UNIV WASHINGTON,DEPT BIOCHEM,SEATTLE,WA 98195

[2] UNIV WASHINGTON,DEPT CHEM,SEATTLE,WA 98195

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1990年 / 15卷 / 04期

关键词：

D O I：

10.1016/0968-0004(90)90213-U

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent studies have indicated that eukaryotic cells contain proteins that are post-translationally modified by long-chain, thioether-linked prenyl groups. These proteins include yeast mating factors, ras proteins and nuclear lamins. The modification occurs on a cysteine residue near the C terminus and appears to initiate a set of additional protein modification reactions that promote attachment of the proteins to specific membranes. © 1990.

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页码：139 / 142

页数：4

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