EVIDENCE THAT CLOSTRIDIUM-PERFRINGENS THETA-TOXIN INDUCES COLLOID-OSMOTIC LYSIS OF ERYTHROCYTES

被引：18

作者：

HARRIS, RW

SIMS, PJ

TWETEN, RK

机构：

[1] UNIV OKLAHOMA,HLTH SCI CTR,DEPT MICROBIOL & IMMUNOL,OKLAHOMA CITY,OK 73190

[2] OKLAHOMA MED RES FDN,CARDIOVASC BIOL RES PROGRAM,OKLAHOMA CITY,OK 73104

来源：

INFECTION AND IMMUNITY | 1991年 / 59卷 / 07期

关键词：

D O I：

10.1128/IAI.59.7.2499-2501.1991

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Clostridium perfringens theta-toxin was shown to lyse target erythrocytes by a colloid-osmotic mechanism. Analysis showed the onset of lysis of erythrocytes by theta-toxin could be temporarily stabilized with 0.3 M sucrose. Flow cytometry analysis of the size distribution of theta-toxin-treated erythrocytes showed swelling of the erythrocytes prior to lysis.

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页码：2499 / 2501

页数：3

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