MUC1 MUCIN MESSENGER-RNA EXPRESSION IN CULTURED HUMAN NASAL AND BRONCHIAL EPITHELIAL-CELLS

被引：43

作者：

HOLLINGSWORTH, MA

BATRA, SK

QI, WN

YANKASKAS, JR

机构：

[1] DUKE UNIV,MED CTR,DIV IMMUNOL,DURHAM,NC 27710

[2] UNIV N CAROLINA,DEPT MED,CHAPEL HILL,NC 27514

来源：

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY | 1992年 / 6卷 / 05期

关键词：

D O I：

10.1165/ajrcmb/6.5.516

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The MUC1 mucin mRNA, for which the cDNA was previously cloned from human breast and pancreatic tissues, was found to be expressed in nasal and bronchial epithelial cell primary cultures from cystic fibrotic, atopic, and normal individuals. Sequence analysis of cDNA clones from the CF/T43 cystic fibrosis nasal epithelial cell line revealed only insignificant differences in the 3' untranslated region of the mRNA when compared with the pancreas and breast mucin cDNAs.

引用

页码：516 / 520

页数：5

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