A MULTIVARIABLE ANALYSIS OF FACTORS GOVERNING THE STEADY-STATE PHARMACOKINETICS OF VALPROIC ACID IN 52 YOUNG EPILEPTICS

被引：30

作者：

HALL, K

OTTEN, N

JOHNSTON, B

IRVINEMEEK, J

LEROUX, M

SESHIA, S

机构：

[1] HLTH SCI CTR, DEPT BIOSTAT, WINNIPEG R3E 0Z3, MANITOBA, CANADA

[2] HLTH SCI CTR, DEPT CLIN CHEM, WINNIPEG R3E 0Z3, MANITOBA, CANADA

[3] HLTH SCI CTR, DEPT PEDIAT, WINNIPEG R3E 0Z3, MANITOBA, CANADA

[4] UNIV MANITOBA, WINNIPEG R3T 2N2, MANITOBA, CANADA

来源：

JOURNAL OF CLINICAL PHARMACOLOGY | 1985年 / 25卷 / 04期

关键词：

D O I：

10.1002/j.1552-4604.1985.tb02836.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

收藏

页码：261 / 268

页数：8

相关论文

共 10 条

[1] VALPROIC ACID DOSAGE AND PLASMA-PROTEIN BINDING AND CLEARANCE
BOWDLE, TA
PATEL, IH
LEVY, RH
WILENSKY, AJ
[J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 1980, 28 (04) : 486 - 492
[2] EFFECT OF PHENYTOIN ON PROTEIN-BINDING OF VALPROIC ACID
BRUNI, J
GALLO, JM
WILDER, BJ
[J]. CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 1979, 6 (04) : 453 - 454
[3] PHARMACOKINETICS OF VALPROIC ACID IN CHILDREN .1. MULTIPLE ANTI-EPILEPTIC DRUG-THERAPY
CLOYD, JC
KRIEL, RL
FISCHER, JH
SAWCHUK, RJ
EGGERTH, RM
[J]. NEUROLOGY, 1983, 33 (02) : 185 - 191
[4] 1ST-DOSE AND STEADY-STATE PHARMACOKINETICS OF VALPROIC ACID IN CHILDREN WITH SEIZURES
HALL, K
OTTEN, N
IRVINEMEEK, J
LEROUX, M
BUDNICK, D
VERMA, M
SESHIA, SS
[J]. CLINICAL PHARMACOKINETICS, 1983, 8 (05) : 447 - 455
[5] KUTT H, 1982, ANTIEPILEPTIC DRUGS
[6] COMPARISON OF GAS-LIQUID-CHROMATOGRAPHY AND EMIT ASSAY FOR SERUM VALPROIC ACID
LEROUX, M
BUDNIK, D
HALL, K
IRVINEMEEK, J
OTTEN, N
SESHIA, S
[J]. CLINICAL BIOCHEMISTRY, 1981, 14 (02) : 87 - 90
[7] LEVY RH, 1982, ANTIEPILEPTIC DRUGS
[8] VALPROIC ACID AND ETHOSUXIMIDE INTERACTION
MATTSON, RH
CRAMER, JA
[J]. ANNALS OF NEUROLOGY, 1980, 7 (06) : 583 - 584
[9] ROSENBAUM MS, 1983, PEDIATRICS, V71, P359
[10] Searle SR., 1971, LINEAR MODELS