SISTER CHROMATID EXCHANGES IN LYMPHOCYTES OF NORMAL AND ALCOHOLIC SUBJECTS

被引：16

作者：

LAZUTKA, JR

DEDONYTE, V

LEKEVICIUS, RK

机构：

[1] Ecological Genetics Laboratory, Vilnius University, Vilnius, 232009

来源：

EXPERIENTIA | 1992年 / 48卷 / 05期

关键词：

SISTER CHROMATID EXCHANGE (SCE); HUMAN LYMPHOCYTES; ALCOHOL CONSUMPTION; SMOKING; AGING;

D O I：

10.1007/BF01928176

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The effects of alcohol consumption, cigarette smoking and age on sister chromatid exchange (SCE) frequency in human lymphocytes were assessed by means of multiple linear regression. An increase in SCE rates was associated with alcohol consumption (p = 0.0001), smoking (p = 0.0231), and, to a small extent (p = 0.057), age. These three confounding factors explain 48 % of the inter-personal variation in SCE rates among subjects studied.

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收藏

页码：508 / 512

页数：5

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