A CONVENIENT, HIGHLY STEREOSELECTIVE SYNTHESIS OF ANTI-ALPHA,BETA-EPOXY ALCOHOLS BY THE LUCHE REDUCTION OF ALPHA,BETA-EPOXY KETONES

被引：25

作者：

LI, KQ ^{[1
]}

HAMANN, LG ^{[1
]}

KOREEDA, M ^{[1
]}

机构：

[1] UNIV MICHIGAN,DEPT CHEM,ANN ARBOR,MI 48109

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 44期

关键词：

D O I：

10.1016/S0040-4039(00)60987-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reduction of alpha,beta-epoxy ketones under the Luche conditions with NaBH4/CeCl3 in MeOH provides anti- (or erythro-) alpha,beta-epoxy alcohols in high yields and with extremely high stereoselectivity.

引用

页码：6569 / 6570

页数：2

共 9 条

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[4] AN EFFICIENT, HIGHLY STEREOSELECTIVE SYNTHESIS OF (Z)-16-ALPHA-HYDROXY-17-ETHYLIDENE STEROIDS
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[6] HIGHLY STEREOSELECTIVE SYNTHESIS OF ERYTHRO-ALPHA, BETA-EPOXY ALCOHOLS BY THE REDUCTION OF ALPHA, BETA-EPOXY KETONES WITH ZINC BOROHYDRIDE
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[J]. TETRAHEDRON LETTERS, 1981, 22 (47) : 4723 - 4726
[7] AN INTRODUCTION OF CHIRAL CENTERS INTO ACYCLIC SYSTEMS BASED ON STEREOSELECTIVE KETONE REDUCTION
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[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1984, 17 (09) : 338 - 344
[8] ROSSITER BE, 1979, TETRAHEDRON LETT, P4733
[9] YOON NM, 1975, J KOREAN CHEM SOC, V19, P355

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