TRANSCRIPTION INITIATION-COMPLEXES AND UPSTREAM ACTIVATION WITH RNA POLYMERASE-II LACKING THE C-TERMINAL DOMAIN OF THE LARGEST SUBUNIT

被引:48
作者
BURATOWSKI, S
SHARP, PA
机构
[1] MIT,CTR CANC RES,CAMBRIDGE,MA 02139
[2] MIT,DEPT BIOL,CAMBRIDGE,MA 02139
关键词
D O I
10.1128/MCB.10.10.5562
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
RNA polymerase II assembles with other factors on the adenovirus type 2 major late promoter to generate pairs of transcription initiation complexes resolvable by nondenaturing gel electrophoresis. The pairing of the complexes is caused by the presence or absence of the C-terminal domain of the largest subunit. This domain is not required for transcription stimulation by the major late transcription factor in vitro.
引用
收藏
页码:5562 / 5564
页数:3
相关论文
共 18 条