EXPRESSION OF THE MURINE DLX-1 HOMEOBOX GENE DURING FACIAL, OCULAR AND LIMB DEVELOPMENT

被引：144

作者：

DOLLE, P ^{[1
]}

PRICE, M ^{[1
]}

DUBOULE, D ^{[1
]}

机构：

[1] EUROPEAN MOLEC BIOL LAB,MEYERHOFSTR 1,POSTFACH 102209,W-6900 HEIDELBERG 1,GERMANY

来源：

DIFFERENTIATION | 1992年 / 49卷 / 02期

关键词：

D O I：

10.1111/j.1432-0436.1992.tb00773.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

We have analysed the expression pattern of the mouse homeobox containing gene Dlx-1. This gene harbors a homeodomain related to that found in the Drosophila distal-less (dll) gene. In addition to its expression in the developing forebrain, Dlx-1 is transcribed in several structures containing cells of neural crest origin such as the facial mesenchyme and various elements of the peripheral nervous system. Dlx-1 transcripts are also detected in the differentiating retina and during limb morphogenesis, in the apical ectodermal ridge. The possible involvement of Dlx-1 during facial, ocular and limb development is discussed.

引用

页码：93 / 99

页数：7

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