STEREOSELECTIVE TOTAL SYNTHESIS OF POLYETHER IONOPHORE ANTIBIOTICS, ISOLASALOCID-A AND LASALOCID-A .1. STEREOCONTROLLED CONSTRUCTION OF THE C-RINGS (C-18-C-24) BY ACID-CATALYZED CYCLIZATION OF P-METHOXYPHENYLALLYL ALCOHOLS

被引：7

作者：

HORITA, K

NODA, I

TANAKA, K

MIURA, T

OIKAWA, Y

YONEMITSU, O

机构：

[1] Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo

来源：

TETRAHEDRON | 1993年 / 49卷 / 27期

关键词：

POLYETHER ANTIBIOTIC; TOTAL SYNTHESIS; STEREOSELECTIVE SYNTHESIS; TETRAHYDROFURAN; TETRAHYDROPYRAN; ACID-CATALYZED CYCLIZATION;

D O I：

10.1016/S0040-4020(01)87184-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The C18-C24 subunits (11, 12) of isolasalocid A (9) and lasalocid A (10) were synthesized stereoselectively via construction of the tetrahydrofuran and tetrahydropyran rings by acid-catalyzed cyclization of the corresponding p-methoxyphenylallyl alcohols (18, 25).

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页码：5979 / 5996

页数：18

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