HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ANALYSIS OF MONOAMINES IN THE CESTODE DIPHYLLOBOTHRIUM-DENDRITICUM

被引：15

作者：

ERIKSSON, K ^{[1
]}

GUSTAFSSON, M ^{[1
]}

AKERLIND, G ^{[1
]}

机构：

[1] ABO AKAD UNIV,DEPT BIOCHEM & PHARM,TURKU,FINLAND

来源：

PARASITOLOGY RESEARCH | 1993年 / 79卷 / 08期

关键词：

D O I：

10.1007/BF00932514

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The presence of biogene monoamines in adult and larval Diphyllobothrium dendriticum (Cestoda) was investigated by high-performance liquid chromatography with electrochemical detection (HPLC-ED). The biogene amines serotonin (5-HT), dopamine (DA), noradrenaline (NA), and adrenaline (A) as well as many of their precursors and metabolites, comprising a total of 15 different substances, were analyzed. 5-HT, DOPA, DA, NA, and A were detected in the worm, with 5-HT, DOPA, and DA being the dominating amines. The DA metabolites DOPAC and 3-MT or the 5-HT precursor 5-hydroxytryptophan could not be detected, but two unidentified substances, believed to be catecholic, were present in the worm. A high concentration of DOPA was measured in the proglottids and especially in the eggs. This is the first report of A in a flatworm.

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页码：699 / 702

页数：4

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