TRANSCRIPTIONAL REPRESSION IN EUKARYOTES

被引：200

作者：

RENKAWITZ, R

机构：

[1] Max-Planck-Institut für Biochemie, D-8033 Martinsried, Genzentrum

来源：

TRENDS IN GENETICS | 1990年 / 6卷 / 06期

关键词：

D O I：

10.1016/0168-9525(90)90176-7

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Gene transcription can be controlled by positive or negative regulatory mechanisms; a combination of both is frequently responsible for the observed expression patterns. Analysis of a number of eukaryotic systems suggests that repressors can interfere with many and perhaps all the steps required for transcriptional activation. Transcriptional repression mechanisms can usefully be divided into three major classes: inhibition of DNA binding blocking of activation and silencing. © 1990.

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页码：192 / 197

页数：6

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