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GLYCOCONJUGATE EXPRESSION DURING EMBRYOGENESIS AND ITS BIOLOGICAL SIGNIFICANCE

被引：189
作者：
FENDERSON, BA
EDDY, EM
HAKOMORI, S
机构：
[1] UNIV WASHINGTON,SEATTLE,WA 98195
[2] NIEHS,RES TRIANGLE PK,NC 27709
来源：
BIOESSAYS | 1990年 / 12卷 / 04期
关键词：
D O I：
10.1002/bies.950120406
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Many stage‐specific embryonic antigens (SSEAs) have been identified as glycoconjugates. These molecules may play diverse roles in the development of the embryo, including regulation of cell growth, recognition, and differentiation. The example of SSEA‐1 is described in detail. This molecule appears to play an essential role in compaction of the early mouse embryo, and may illustrate the general importance of carbohydrate‐carbohydrate interactions in controlling cell surface interactions in development. Copyright © 1990 Cambridge University Press
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页码：173 / 179
页数：7
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