AN EXPLANATION OF ANOMALOUS ARTIFACT INTENSITY IN FULLY H-1 H-1 DECOUPLED 2-DIMENSIONAL CHEMICAL-SHIFT CORRELATION SPECTROSCOPY

被引：4

作者：

BAIN, AD ^{[1
]}

BURTON, IW ^{[1
]}

CARPENTER, K ^{[1
]}

REYNOLDS, WF ^{[1
]}

机构：

[1] UNIV TORONTO,DEPT CHEM,TORONTO M5S 1A1,ONTARIO,CANADA

来源：

MAGNETIC RESONANCE IN CHEMISTRY | 1991年 / 29卷 / 04期

关键词：

FULLY H-1 H-1 DECOUPLED 2D SHIFT CORRELATION SPECTROSCOPY; EXPLANATION OF ANOMALOUS ARTIFACT INTENSITY; COLOC AND HETRES EXPERIMENTS;

D O I：

10.1002/mrc.1260290406

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two-dimensional heteronuclear chemical shift correlation experiments which attempt decoupling in f1 have been shown to give artifacts in strongly coupled systems. In particular, COLOC and HETRES experiments on methylene groups show an artifact midway between the two proton lines. This paper provides an explanation of the artifact intensity behaviour with respect to the strength of coupling between the methylene protons. Experimental results on 1,2-dibromoethylbenzene are presented, and theoretical calculations were carried out on the COLOC experiment and a mathematical model was developed which predicted the artifact appearance and intensity. Simulations were also performed using the simulation program SIMPLTN to verify the experimental and theoretical results.

引用

页码：316 / 322

页数：7

共 36 条

[1] AN INVESTIGATION OF THE EFFECT OF DIGITAL RESOLUTION ON THE COSY TWO-DIMENSIONAL NMR EXPERIMENT BY COMPUTER-SIMULATION [J].