PORPHYRINYL-NUCLEOSIDES CONTAINING FLUORINATED NUCLEOBASES

被引：13

作者：

CZUCHAJOWSKI, L

PALKA, A

MORRA, M

WANDREKAR, V

机构：

[1] Department of Chemistry, University of Idaho, Moscow

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 34期

关键词：

PORPHYRIN; FLUORINATED NUCLEOSIDES; PORPHYRINYL-GUANOSINE;

D O I：

10.1016/S0040-4039(00)73921-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Porphyrins were synthesized in which a meso-p-phenylene-0- bridge joins the porphine core with 6-C of 5-fluorouridine (protected), 5-CF3-thymidine or 2-N-trifluoroacetamidato-6-0-pentafluorophenyl-2'-deoxyguanosine.

引用

页码：5409 / 5412

页数：4

共 17 条

[1]

ADAMIAK RW, 1986, CHEM SCRIPTA, V26, P7

[2] SYNTHESIS AND BIOLOGICAL-ACTIVITY OF 5'-SUBSTITUTED 5-FLUOROPYRIMIDINE NUCLEOSIDES [J].

AJMERA, S ;

DANENBERG, PV .

JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (08) :999-1002

[3] 3',3'-DIFLUORO-3'-DEOXYTHYMIDINE - COMPARISON OF ANTI-HIV ACTIVITY TO 3'-FLUORO-3'-DEOXYTHYMIDINE [J].

BERGSTROM, DE ;

MOTT, AW ;

DECLERCQ, E ;

BALZARINI, J ;

SWARTLING, DJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (18) :3369-3372

[4] SYNTHESIS AND BIOLOGICAL ACTIVITY OF DINUCLEOSIDE PHOSPHATES CONTAINING 5-FLUOROURACIL RESIDUES [J].

BLOCH, A ;

FLEYSHER, MH ;

THEDFORD, R ;

MAUE, RJ ;

HALL, RH .

JOURNAL OF MEDICINAL CHEMISTRY, 1966, 9 (06) :886-&

[5]

CZUCHAJOWSKI L, 1992, BIOORG MED CHEM LETT, V2, P1645

[6] SYNTHESIS OF PORPHYRINYL-NUCLEOSIDES [J].

CZUCHAJOWSKI, L ;

HABDAS, J ;

NIEDBALA, H ;

WANDREKAR, V .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1992, 29 (02) :479-486

[7] PORPHYRINYL-URIDINES AS THE 1ST WATER-SOLUBLE PORPHYRINYL-NUCLEOSIDES [J].

CZUCHAJOWSKI, L ;

HABDAS, J ;

NIEDBALA, H ;

WANDREKAR, V .

TETRAHEDRON LETTERS, 1991, 32 (51) :7511-7512

[8]

CZUCHAJOWSKI L, 1993, 206 NAT ACS M CHIC

[9]

CZUCHAJOWSKI L, UNPUB

[10]

FATHI R, 1990, TETRAHEDRON LETT, V31, P319

← 1 2 →