机构:Department of Parasitology, The Hebrew University, Hadassah Medical School, Jerusalem
SHLOMAI, J
机构:
[1] Department of Parasitology, The Hebrew University, Hadassah Medical School, Jerusalem
来源:
PARASITOLOGY TODAY
|
1994年
/
10卷
/
09期
基金:
以色列科学基金会;
关键词:
D O I:
10.1016/0169-4758(94)90244-5
中图分类号:
R38 [医学寄生虫学];
Q [生物科学];
学科分类号:
07 ;
0710 ;
09 ;
100103 ;
摘要:
The unusual structure of the kinetoplast DNA (kDNA) of trypanosomatids requires unique replication mechanisms. Deciphering the mechanisms that regulate the network assembly has been a challenge for many years. A better understanding of these processes was facilitated by recent studies on the fine structure of resting and replicating kDNA networks. In this review, Joseph Shlomai discusses our current view of the structural and mechanistic aspects of the assembly of kinetoplast DNA.