A SIMPLIFIED METHOD FOR LARGE-SCALE HPA-1A PHENOTYPING FOR ANTENATAL SCREENING

被引：11

作者：

METCALFE, P

DOUGHTY, HA

MURPHY, MF

WATERS, AH

机构：

[1] Department of Haematology, St Bartholomew's Hospital and Medical College, London

来源：

TRANSFUSION MEDICINE | 1994年 / 4卷 / 01期

关键词：

ALLOIMMUNE THROMBOCYTOPENIA; ANTENATAL SCREENING; HPA-1A; MAIPA;

D O I：

10.1111/j.1365-3148.1994.tb00239.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A simplified method for large-scale HPA-1a phenotyping of platelets was developed for use in an antenatal screening programme for fetomaternal alloimmune thrombocytopenia (FMAIT). The test was based on the MAIPA assay, which was modified for antigen-typing with a well-characterized anti-HPA-1a reagent. The resulting assay gave reliable results, was inexpensive and allowed testing of large batches using semiautomated equipment.

引用

页码：21 / 24

页数：4

共 16 条

[1] IMMUNOCHEMICAL CHARACTERIZATION OF A NEW PLATELET SPECIFIC MONOCLONAL-ANTIBODY AND ITS USE TO DEMONSTRATE THE CYTOSKELETAL ASSOCIATION OF THE PLATELET GLYCOPROTEIN-IIB-IIIA COMPLEX [J].