Enhancing the immune response through next generation polymeric vaccine adjuvants
被引:8
作者:
Adams, Justin R.
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机构:
Iowa State Univ, Dept Chem & Biol Engn, Ames, IA 50011 USAIowa State Univ, Dept Chem & Biol Engn, Ames, IA 50011 USA
Adams, Justin R.
[1
]
Mallapragada, Surya K.
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机构:
Iowa State Univ, Dept Chem & Biol Engn, Ames, IA 50011 USAIowa State Univ, Dept Chem & Biol Engn, Ames, IA 50011 USA
Mallapragada, Surya K.
[1
]
机构:
[1] Iowa State Univ, Dept Chem & Biol Engn, Ames, IA 50011 USA
来源:
TECHNOLOGY
|
2014年
/
2卷
/
01期
关键词:
D O I:
10.1142/S2339547814300017
中图分类号:
T [工业技术];
学科分类号:
08 [工学];
摘要:
The search for improved vaccine adjuvants has intensifi ed recently with the growing popularity of subunit vaccines. These vaccines can induce efficient antibody response and cellular immunity without the safety constraints of live vaccines, but must overcome their poor immunogenicity. Next-generation vaccine adjuvants offer several advantages over conventional adjuvants and can be rationally designed to meet the requirements of the antigen. This review analyzes current research in the field of vaccine adjuvant design, with an emphasis on polymeric vaccine adjuvants.
机构:
Inst Pasteur, Aspergillus Unit, F-75015 Paris, FranceINSERM, U872, F-75006 Paris, France
Aimanianda, Vishukumar
;
Haensler, Jean
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机构:
Sanofi Pasteur, Res Dept, F-69280 Marcy Letoile, FranceINSERM, U872, F-75006 Paris, France
Haensler, Jean
;
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机构:
Lacroix-Desmazes, Sebastien
;
Kaveri, Srini V.
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机构:
INSERM, U872, F-75006 Paris, France
Univ Paris 06, Ctr Rech Cordeliers, Equipe Immunopathol & Therapeut Immunointervent 1, UMR S 872, F-75006 Paris, France
Univ Paris 05, UMR S 872, F-75006 Paris, FranceINSERM, U872, F-75006 Paris, France
Kaveri, Srini V.
;
Bayry, Jagadeesh
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h-index: 0
机构:
INSERM, U872, F-75006 Paris, France
Univ Paris 06, Ctr Rech Cordeliers, Equipe Immunopathol & Therapeut Immunointervent 1, UMR S 872, F-75006 Paris, France
Univ Paris 05, UMR S 872, F-75006 Paris, FranceINSERM, U872, F-75006 Paris, France
机构:
Inst Pasteur, Aspergillus Unit, F-75015 Paris, FranceINSERM, U872, F-75006 Paris, France
Aimanianda, Vishukumar
;
Haensler, Jean
论文数: 0引用数: 0
h-index: 0
机构:
Sanofi Pasteur, Res Dept, F-69280 Marcy Letoile, FranceINSERM, U872, F-75006 Paris, France
Haensler, Jean
;
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h-index:
机构:
Lacroix-Desmazes, Sebastien
;
Kaveri, Srini V.
论文数: 0引用数: 0
h-index: 0
机构:
INSERM, U872, F-75006 Paris, France
Univ Paris 06, Ctr Rech Cordeliers, Equipe Immunopathol & Therapeut Immunointervent 1, UMR S 872, F-75006 Paris, France
Univ Paris 05, UMR S 872, F-75006 Paris, FranceINSERM, U872, F-75006 Paris, France
Kaveri, Srini V.
;
Bayry, Jagadeesh
论文数: 0引用数: 0
h-index: 0
机构:
INSERM, U872, F-75006 Paris, France
Univ Paris 06, Ctr Rech Cordeliers, Equipe Immunopathol & Therapeut Immunointervent 1, UMR S 872, F-75006 Paris, France
Univ Paris 05, UMR S 872, F-75006 Paris, FranceINSERM, U872, F-75006 Paris, France