FIBRINOUS REACTION ON IMPLANTED INTRAOCULAR LENSES - A COMPARISON OF CONVENTIONAL PMMA AND HEPARIN SURFACE MODIFIED LENSES

被引：17

作者：

LUNDGREN, B

SELEN, G

SPANGBERG, M

HARFSTRAND, A

机构：

[1] Kabi Pharmacia Ophthalmics, Department of Biology, Uppsala

[2] Kabi Pharmacia Therapeutics, Department of Toxicology, Uppsala

[3] Karolinska Institute, Department of Histology and Neurobiology, Stockholm

来源：

JOURNAL OF CATARACT AND REFRACTIVE SURGERY | 1992年 / 18卷 / 03期

关键词：

CATARACT SURGERY; FIBRINOUS REACTION; HEPARIN SURFACE MODIFICATION; INTRAOCULAR LENS; MONKEY EYE; POLY(METHYL METHACRYLATE);

D O I：

10.1016/S0886-3350(13)80899-1

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

We studied the fibrinous reaction after intraocular lens (IOL) implantation in the posterior chamber of cynomolgus monkeys. In 50% of the eyes, we implanted an IOL made of conventional poly(methyl methacrylate) (PMMA); in the remaining eyes we implanted a PMMA IOL with a heparin modified surface. Two, 4, 8, and 18 weeks after surgery the eyes were examined by slitlamp for fibrinous reactions on and around the IOL surface. At weeks 4, 8, and 18 there was a marked decrease in fibrinous reaction in the eyes with a heparin surface modified IOL. The results of this study accord with earlier findings that heparin surface modification improves the biocompatibility of the IOL.

引用

页码：236 / 239

页数：4

共 22 条

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