FLUIDITY-DEPENDENT MG-2+-ATPASE ACTIVITY IN MEMBRANES FROM LEISHMANIA-DONOVANI PROMASTIGOTES

被引：7

作者：

DUTTA, M ^{[1
]}

BANDYOPADHYAY, R ^{[1
]}

GHOSH, C ^{[1
]}

BASU, MK ^{[1
]}

机构：

[1] INDIAN INST CHEM BIOL,DIV BIOMEMBRANE,LEISHMANIA GRP,CALCUTTA 700032,W BENGAL,INDIA

来源：

BIOCHEMICAL JOURNAL | 1990年 / 265卷 / 03期

关键词：

D O I：

10.1042/bj2650923

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The state of the lipid phase of the membrane plays a key role in the exposure of various receptors, antigens and enzymes on the membrane surface. The fluidity of membranes of Leishmania donovani promastigotes was monitored by two independent methods, i.e. influx of sterol from liposomes and removal of phospholipids by treatment with phospholipase C. The altered sterol/phospholipid ratio in both cases, provided evidence that the activity of the functionally important membrane-bound enzyme Mg2+-ATPase is modulated by the state of the lipid phase of the membrane.

引用

页码：923 / 926

页数：4

共 27 条

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