HETERONUCLEAR J-COUPLING MODULATION AS AN IMAGING METHOD FOR NUCLEI IN LOW CONCENTRATION

被引：9

作者：

DELUCA, F

CAMPANELLA, R

BIFONE, A

MARAVIGLIA, B

机构：

[1] Dipartimento di Fisica, Università degli Studi La Sapienza

来源：

JOURNAL OF MAGNETIC RESONANCE | 1991年 / 93卷 / 03期

关键词：

D O I：

10.1016/0022-2364(91)90082-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A double-resonance imaging method for nuclei in low concentration is presented. The method utilizes the scalar coupling between the low-concentration spin and an abundant or more sensitive spin species. The spatial position of the low-concentration spin is located by identifying all the abundant spins J-coupled to it. The method was tested on CH2FCH2OH, in which the fluorine played the role of the low-density nucleus. The results show that the fluorine nucleus is spatially localized with a signal-to-noise ratio given by its J-coupled 1H nuclei. © 1991.

引用

页码：554 / 562

页数：9

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