SYNTHETIC STUDIES ON (-)-TETRODOTOXIN .3. NITROGENATION THROUGH OVERMAN REARRANGEMENT AND GUANIDINE RING FORMATION

被引:39
作者
ISOBE, M [1 ]
FUKUDA, Y [1 ]
NISHIKAWA, T [1 ]
CHABERT, P [1 ]
KAWAI, T [1 ]
GOTO, T [1 ]
机构
[1] EISAI & CO LTD, TSUKUBA RES LABS, IBARAKI 30026, JAPAN
关键词
D O I
10.1016/S0040-4039(00)89056-5
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The guanidinium part of tetrodotoxin was synthesized from a sugar derivative, levoglucosenone, in optically active form via Overman rearrangement as key step. © 1990.
引用
收藏
页码:3327 / 3330
页数:4
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