THE INITIATION OF CHROMOSOMAL DNA-REPLICATION IN EUKARYOTES

被引:32
作者
DIFFLEY, JFX [1 ]
STILLMAN, B [1 ]
机构
[1] COLD SPRING HARBOR LAB, COLD SPRING HARBOR, NY 11724 USA
关键词
D O I
10.1016/0168-9525(90)90305-P
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Eukaryotic DNA replication initiates at many sites on each chromosome during the S phase of the cell cycle. Each origin of replication lies in a unique chromosomal environment and can be regulated in different cell types both at the level of utilization and the time of initiation during S phase. In this review, we examine the control and the mechanism of eukaryotic origin function. © 1990.
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页码:427 / 432
页数:6
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