PREPARATION OF POTENTIAL ANTIINFLAMMATORY AGENTS FROM DEHYDROABIETIC ACID

被引：11

作者：

LI, WS ^{[1
]}

MCCHESNEY, JD ^{[1
]}

机构：

[1] UNIV MISSISSIPPI,DEPT PHARMACOGNOSY,UNIVERSITY,MS 38677

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1992年 / 81卷 / 07期

关键词：

D O I：

10.1002/jps.2600810711

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Methyl 16-nor-16-carboxydehydroabietate (22), 16-nor-16-carboxydehydroabietinol acetate (23), methyl 7-keto-16-nor-16-carboxydehydroabietate (29), 16-nor-16-carboxydehydroabietic acid (30), 16-nor-16-carboxydehydroabietinol (31), 7-keto-16-nor-16-carboxydehydroabietic acid (32), methyl 7-hydroxy-16-nor-16-carboxydehydroabietate (33), and 7-hydroxy-16-nor-16-carboxydehydroabietic acid (34) were prepared from dehydroabietic acid. Only 22 and 32 had weak anti-inflammatory activity.

引用

页码：646 / 651

页数：6

共 13 条

[1] HYDROBORATION .36. DIRECT ROUTE TO 9-BORABICYCLO[3.3.1]NONANE VIA CYCLIC HYDROBORATION OF 1,5-CYCLOOCTADIENE - 9-BORABICYCLO[3.3.1]NONANE AS A UNIQUELY SELECTIVE REAGENT FOR HYDROBORATION OF OLEFINS [J].