SPECIFIC INHIBITORS FOR THE GLYCOLYTIC-ENZYMES OF TRYPANOSOMA-BRUCEI

被引：10

作者：

TRINQUIER, M

PERIE, J

CALLENS, M

OPPERDOES, F

WILLSON, M

机构：

[1] UNIV TOULOUSE 3, CHIM ORGAN BIOL GRP, URA 470, F-31062 TOULOUSE, FRANCE

[2] UNIV CATHOLIQUE LOUVAIN, INT INST CELLULAR & MOLEC PATHOL, BIOCHEM LAB, TROP DIS RES UNIT, B-12000 BRUSSELS, BELGIUM

来源：

BIOORGANIC & MEDICINAL CHEMISTRY | 1995年 / 3卷 / 11期

关键词：

D O I：

10.1016/0968-0896(95)00129-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The selective inhibition of four glycolytic enzymes from Trypanosoma brucei by alpha-omega difunctionalized compounds at clusters of amino acids exhibit higher activity than the trypanocidal drug suramin.

引用

页码：1423 / 1427

页数：5

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