RAT LUNG-TISSUE IS A SITE OF ALPHA-1-PROTEINASE INHIBITOR SYNTHESIS - EVIDENCE BY CELL-FREE TRANSLATION

被引：5

作者：

BUDEK, W

BUNNING, P

HEINRICH, PC

机构：

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1984年 / 122卷 / 01期

关键词：

D O I：

10.1016/0006-291X(84)90488-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Poly(A)+RNA isolated from lungs of normal rats and of rats suffering from experimental inflammation was translated in a cell-free translation mixture from rabbit reticulocytes. The translation products were immunoprecipitated with specific antisera against .alpha.1-proteinase inhibitor and .alpha.2-macroglobulin. Comparable levels of mRNA for .alpha.1-proteinase inhibitor were found in rat lung tissue from control and experimentally inflamed animals. .alpha.2-Macroglobulin mRNA could not be detected in rat lung tissue.

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页码：394 / 400

页数：7

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