STRUCTURE-ACTIVITY-RELATIONSHIPS OF 2,3-BENZODIAZEPINE COMPOUNDS WITH GLUTAMATE ANTAGONISTIC ACTION

被引：70

作者：

TARNAWA, I

BERZSENYI, P

ANDRASI, F

BOTKA, P

HAMORI, T

LING, I

KOROSI, J

机构：

[1] Institute for Drug Research, H-1325 Budapest

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 01期

关键词：

D O I：

10.1016/S0960-894X(00)80100-6

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of N-substituted 1-(4'-aminophenyl)-4-methyl-3,4-dihydro-7,8-methylene-dioxy-5H-2,3-benzodiazepines, structural analogues of the selective non-NMDA antagonist GYKI 52466, has been synthesized and tested for biological activity, in vivo and in vitro.

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页码：99 / 104

页数：6

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