LIGHT AND ELECTRON-MICROSCOPIC STUDY OF REMODELING AND MATURATION PROCESS IN AUTOGENOUS GRAFT FOR ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION

被引：100

作者：

ABE, S ^{[1
]}

KUROSAKA, M ^{[1
]}

IGUCHI, T ^{[1
]}

YOSHIYA, S ^{[1
]}

HIROHATA, K ^{[1
]}

机构：

[1] KOBE UNIV,SCH MED,DEPT ORTHOPAED SURG,7-5 KUSUNOKICHO,CHUO KU,KOBE 650,JAPAN

来源：

ARTHROSCOPY | 1993年 / 9卷 / 04期

关键词：

ANTERIOR CRUCIATE LIGAMENT; RECONSTRUCTION; REMODELING;

D O I：

10.1016/S0749-8063(05)80313-5

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

We evaluated the remodeling process of autogenous patellar tendon graft for anterior cruciate ligament (ACL) reconstruction by means of light microscopic (LM) and electron microscopic (EM) examinations from the biopsy specimens obtained at the time of second-look arthroscopy. Twenty-one patients were examined at various times postoperatively (from 6 weeks to 15 months, mean 9.5 months), and the results were cor-related with the morphology of normal patellar tendon and normal ACL. Our study showed that the graft was revascularized in the early postoperative period, fibroblastic remodeling took place, and the graft obtained gross similarity to the original ACL on their arthroscopic and LM appearances at approximately 1 year postoperatively. However, EM study showed that at both approximately 6 months and 1 year postoperatively the grafts consisted equally of active fibroblasts with a higher cytoplasm-to-nucleus ratio compared with normal ACL. Collagen fibrils of these grafts were of uniformly small diameter compared with normal patellar tendon and ACL. Our results with ultrastructural study suggest that the grafts were still immature even at 1 year postoperatively.

引用

页码：394 / 405

页数：12

共 35 条

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