TESTING FOR THE TOXICITY OF CHEMICALS WITH TETRAHYMENA-PYRIFORMIS

被引:41
作者
YOSHIOKA, Y [1 ]
OSE, Y [1 ]
SATO, T [1 ]
机构
[1] GIFU PHARMACEUT UNIV,GIFU 502,JAPAN
关键词
MARINE BIOLOGY;
D O I
10.1016/0048-9697(85)90037-3
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
A test was developed using Tetrahymena pyriformis in order to determine the toxicity of various chemicals. Pre-cultured T. pyriformis was exposed for 24 h at 30 degree C to various concentrations of chemicals, and the number of T. pyriformis surviving were then counted. The concentration of the chemical, at which the proliferation of T. pyriformis was restricted to one-half of the blank test EC//5//0), was determined. The method, applied to 57 chemicals, demonstrated that it could be used to detect the chemicals at low concentrations rapidly and with ease. The EC//5//0 values showed a good relationship with 48 h LC//5//0 values for Himedaka (Orizias latipes), and could be explained on the basis of the partition between water and n-octanol.
引用
收藏
页码:149 / 157
页数:9
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