NEURONS IN THE AREA OF HUMAN THALAMIC NUCLEUS VENTRALIS CAUDALIS RESPOND TO PAINFUL HEAT STIMULI

被引：89

作者：

LENZ, FA ^{[1
]}

SEIKE, M ^{[1
]}

LIN, YC ^{[1
]}

BAKER, FH ^{[1
]}

ROWLAND, LH ^{[1
]}

GRACELY, RH ^{[1
]}

RICHARDSON, RT ^{[1
]}

机构：

[1] NIDR,NEUROBIOL & ANESTHESIOL BRANCH,BETHESDA,MD 20892

来源：

BRAIN RESEARCH | 1993年 / 623卷 / 02期

关键词：

PAIN; HUMAN THALAMUS; VENTRAL POSTERIOR NUCLEUS; MICROSTIMULATION; WIDE DYNAMIC RANGE CELL; HIGH THRESHOLD CELL; SINGLE NEURON ANALYSIS; THERMORECEPTION;

D O I：

10.1016/0006-8993(93)91433-S

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A population of neurons in the area of human thalamic nucleus ventralis caudalis (Vc) respond to noxious heat stimuli. In the cutaneous co,e of Vc 6% (6/108) of recorded neurons had a significantly greater response to noxious heat stimuli than to innocuous control stimuli. Half of these neurons (n = 3) also responded to innocuous cold stimuli. Within the region posterior and inferior to the' cutaneous core of Vc 5% (4/77) of neurons responded exclusively to noxious heat stimuli. Cells responding to noxious heat were recorded at a greater proportion (66%) of sites where painful sensations were evoked by microstimulation than at sites where nonpainful sensations were evoked (1.5%). The results suggest that neurons in the region of human Vc mediate the sensory aspect of pain.

引用

页码：235 / 240

页数：6

共 50 条

[1]

APKARIAN A V, 1991, Society for Neuroscience Abstracts, V17, P838

[2] PRIMATE SPINOTHALAMIC PATHWAYS .2. THE CELLS OF ORIGIN OF THE DORSOLATERAL AND VENTRAL SPINOTHALAMIC PATHWAYS [J].