Calcaneal BMD Obtained by Dual X-Ray and Laser Predicts Future Hip Fractures-A Prospective Study on 4 398 Swedish Women

被引:8
作者
Brismar, Torkel B. [1 ]
Janszky, Imre [2 ]
Toft, L. I. M. [1 ,3 ,4 ]
机构
[1] Karolinska Univ Hosp, Karolinska Inst, Dept Clin Sci Intervent & Technol, Div Radiol, S-14186 Stockholm, Sweden
[2] Karolinska Inst, Dept Publ Hlth Sci, Div Publ Hlth Epidemiol, S-17177 Stockholm, Sweden
[3] Merck Sharp & Dohme Ltd, S-19278 Sollentuna, Sweden
[4] Pfizer AB, S-19190 Stockholm, Sollentuna, Sweden
关键词
D O I
10.4061/2010/875647
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
The predictive value of dual X-ray and laser (DXL) calcaneal BMD (BMDDXL) on hip fractures was prospectively studied in 4,398 females aged 55 to 99 years. The average follow-up period was 3 years and 11 months with a total of 17,270 person years. Fractures were identified from the national patient register. After inclusion, 130 females sustained a hip fracture. The age adjusted hazard ratio for T-score < -2.5 versus > -2.5 was 2.64. Of all patients who sustained a hip fracture 78% had a T-score of -2.5 or below. The annual hip fracture rate was 0.26% at T-scores >= -2, but 1.5% at T-scores <= -2.5. The area under curve for the model including calcaneal BMDDXL, follow-up time, and age to prospectively predict hip fractures was 0.84. Conclusions. Calcaneal BMDDXL obtained by DXL Calscan predicts hip fractures and may therefore be suitable for diagnosing osteoporosis and for predicting fracture risk.
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