SELECTIVE DIGESTIVE DECONTAMINATION IN MULTIPLE TRAUMA PATIENTS - COST AND EFFICACY

被引：17

作者：

LANGLOISKARAGA, A ^{[1
]}

BUESCHARBIT, M ^{[1
]}

DAVIGNON, A ^{[1
]}

ALBANESE, J ^{[1
]}

DURBEC, O ^{[1
]}

MARTIN, C ^{[1
]}

MORATI, N ^{[1
]}

BALANSARD, G ^{[1
]}

机构：

[1] HOP NORD MARSEILLE,MED INFORMAT UNIT,MARSEILLE,FRANCE

来源：

PHARMACY WORLD & SCIENCE | 1995年 / 17卷 / 01期

关键词：

ANTIBIOTICS; BACTERIA; CLINICAL TRIALS; COSTS AND COST ANALYSIS; DRUG UTILIZATION; INFECTION; MULTIPLE TRAUMA; SELECTIVE DIGESTIVE DECONTAMINATION;

D O I：

10.1007/BF01875552

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A double-blind randomized placebo-controlled study was carried out to evaluate the efficacy and the cost of selective digestive decontamination (SDD) to prevent nosocomial pneumonia in multiple-trauma patients. Nosocomial infections, particularly pneumonia, were mere frequent in the placebo group. The most common infectious agent was Staphylococcus: Staphylococcus aureus in the placebo group and Staphylococcus epidermidis in the SDD group. Methicillin-resistant. Staphylococcus epidermidis was detected more often in the SDD group. No methicillin-resistant Staphylococcus aureus was observed in this study. Fewer patients in the SDD group required antibiotherapy. SDD resulted in a saving of about 41% in drug expenditure.

引用

页码：12 / 16

页数：5

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