EPIDERMOLYTIC HYPERKERATOSIS - GENERALIZED FORM IN CHILDREN FROM PARENTS WITH SYSTEMATIZED LINEAR FORM

被引：49

作者：

NAZZARO, V ^{[1
]}

ERMACORA, E ^{[1
]}

SANTUCCI, B ^{[1
]}

CAPUTO, R ^{[1
]}

机构：

[1] OSPED S GALLICANO,ROME,ITALY

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1990年 / 122卷 / 03期

关键词：

D O I：

10.1111/j.1365-2133.1990.tb08292.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Two unrelated families are presented in both of which a child with generalized epidermolytic hyperkeratosis (congenital bullous ichthyosiform erythroderma) had a parent with linear epidermolytic hyperkeratosis (epidermolytic epidermal naevus). Light and electron microscopy of skin biopsies of lesions from the children and parent showed typical epidermolytic hyperkeratosis. Gonadal mosaicism in patients with linear epidermolytic hyperkeratosis may be responsible for transmission of the abnormality to the offspring.

引用

收藏

页码：417 / 422

页数：6

相关论文

共 16 条

[1] HISTOPATHOLOGIC CONCEPT OF EPIDERMOLYTIC HYPERKERATOSIS [J].

ACKERMAN, AB .

ARCHIVES OF DERMATOLOGY, 1970, 102 (03) :253-&

[2] ULTRASTRUCTURE OF INBORN ERRORS OF KERATINIZATION .2. ICHTHYOSIS HYSTRIX TYPE CURTH-MACKLIN [J].

ANTONLAMPRECHT, I ;

CURTH, HO ;

SCHNYDER, UW .

ARCHIV FUR DERMATOLOGISCHE FORSCHUNG, 1973, 246 (01) :77-91

[3] GENETICALLY INDUCED ABNORMALITIES OF EPIDERMAL DIFFERENTIATION AND ULTRASTRUCTURE IN ICHTHYOSES AND EPIDERMOLYSES - PATHOGENESIS, HETEROGENEITY, FETAL MANIFESTATION, AND PRENATAL-DIAGNOSIS [J].

ANTONLAMPRECHT, I .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1983, 81 (01) :S149-S156

[4] BULLOUS CONGENITAL ICHTHYOSIFORM ERYTHRODERMA [J].

BARKER, LP ;

SACHS, W .

AMA ARCHIVES OF DERMATOLOGY AND SYPHILOLOGY, 1953, 67 (05) :443-455

[5]

BLANCHETBARDON C, IN PRESS J AM ACAD D

[6] PRENATAL-DIAGNOSIS OF BULLOUS ICHTHYOSIFORM ERYTHRODERMA - DETECTION OF TONOFILAMENT CLUMPS IN FETAL EPIDERMAL AND AMNIOTIC-FLUID CELLS [J].

EADY, RAJ ;

GUNNER, DB ;

CARBONE, LDL ;

BRICARELLI, FD ;

GOSDEN, CM ;

RODECK, CH .

JOURNAL OF MEDICAL GENETICS, 1986, 23 (01) :46-51

[7] ICHTHYOSIFORM DERMATOSES [J].

FROST, P ;

VANSCOTT, EJ .

ARCHIVES OF DERMATOLOGY, 1966, 94 (02) :113-&

[8] PRENATAL-DIAGNOSIS OF CONGENITAL BULLOUS ICHTHYOSIFORM ERYTHRODERMA (EPIDERMOLYTIC HYPER-KERATOSIS) BY FETAL SKIN BIOPSY [J].

GOLBUS, MS ;

SAGEBIEL, RW ;

FILLY, RA ;

GINDHART, TD ;

HALL, JG .

NEW ENGLAND JOURNAL OF MEDICINE, 1980, 302 (02) :93-95

[9] EPIDERMOLYTIC PALMOPLANTAR KERATODERMA OF VORNER - IS IT THE MOST FREQUENT TYPE OF HEREDITARY PALMOPLANTAR KERATODERMA [J].

HAMM, H ;

HAPPLE, R ;

BUTTERFASS, T ;

TRAUPE, H .

DERMATOLOGICA, 1988, 177 (03) :138-145

[10] CUTANEOUS MANIFESTATION OF LETHAL GENES [J].

HAPPLE, R .

HUMAN GENETICS, 1986, 72 (03) :280-280