LIGAND-BINDING TO ADENOSINE-A1-RECEPTORS IS INFLUENCED BY PROTONATION

被引：4

作者：

HOPPE, E

REDDINGTON, M

机构：

[1] Department of Neuromorphology, Max Planck Institute for Psychiatry

来源：

NUCLEOSIDES & NUCLEOTIDES | 1991年 / 10卷 / 05期

关键词：

D O I：

10.1080/07328319108047255

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Studies on the pH dependence of ligand binding to A1 adenosine receptors revealed that protonation of a histidine residue in the binding pocket is accompanied by high affinity agonist binding.

引用

页码：1139 / 1140

页数：2