CLONING OF A LOCUSTA CDNA-ENCODING NEUROPARSIN-A

被引：25

作者：

LAGUEUX, M ^{[1
]}

KROMER, E ^{[1
]}

GIRARDIE, J ^{[1
]}

机构：

[1] UNIV BORDEAUX 1,NEUROENDOCRINOL LAB,UNITE RECH ASSOCIEE,F-33405 TALENCE,FRANCE

来源：

INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY | 1992年 / 22卷 / 06期

关键词：

NEUROPARSIN-A; CDNA CLONING; LOCUSTA-MIGRATORIA; NEUROHORMONE PROCESSING;

D O I：

10.1016/0965-1748(92)90027-C

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Brains of larvae and adults of Locusta migratoria produce large amounts of 1 kb transcripts which encode a 107-residue precursor protein for neuroparsin A. The mature neurohormone is processed from this precursor most probably in two steps: (1) cleavage of a 22-residue signal peptide by a signal peptidase; (2) removal of a Glu-Arg dipeptide by a dipeptidase. No additional peptide sequence is present in the neuroparsin precursor. Transcripts encoding neuroparsin A are observed both in larval and adults brains without obvious fluctuations of the transcriptional profiles in relation to development or reproduction.

引用

页码：511 / 516

页数：6

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