2-(N-METHYLANILINO)-2-PHENYLTHIOACETONITRILE - A USEFUL REAGENT FOR PREPARATION OF CONJUGATED ALPHA-AMINO ALKENENITRILES VIA TANDEM ALKYLATION AND DEHYDROSULPHENYLATION

被引：8

作者：

FANG, JM

CHEN, CC

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 12期

关键词：

D O I：

10.1039/p19900003365

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Alkylation of the anion of 2-(N-methylanilino)-2-phenylthioacetonitrile 1 with halogenoalkanes resulted in concurrent elimination of benzenethiol to give conjugated alpha-aminoalkenenitriles of 2E-configuration. Counterattack by bromide and benzenethiolate ions was observed in the prolonged reactions of 1 with 1,4-dibromobut-2-ene and 3-bromo-1-(trimethylsilyl)prop-1-yne.

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页码：3365 / 3367

页数：3

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