PREMATURE LUTEINIZATION - TREATMENT AND INCIDENCE IN NATURAL CYCLES

被引：32

作者：

CHECK, JH ^{[1
]}

CHASE, JS ^{[1
]}

NOWROOZI, K ^{[1
]}

DIETTERICH, CJ ^{[1
]}

机构：

[1] UNIV MED & DENT NEW JERSEY,COOPER HOSP UNIV MED CTR,ROBERT WOOD JOHNSON MED SCH,CAMDEN,NJ

来源：

HUMAN REPRODUCTION | 1991年 / 6卷 / 02期

关键词：

NATURAL CYCLES; PREMATURE LUTEINIZATION; PROGESTERONE;

D O I：

10.1093/oxfordjournals.humrep.a137303

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The incidence of premature luteinization was evaluated in 400 women with a history of infertility (greater-than-or-equal-to 18 months). After its diagnosis, this condition was treated with ovulation-inducing drugs in the early follicular phase in an attempt to accelerate follicular maturation before the luteinizing hormone (LH) surge. Premature luteinization was diagnosed if serum progesterone levels > 1.5 ng/ml were associated with an LH surge before the serum oestradiol level reached 200 pg/ml and before the follicle was mature. Fifty-two of 400 (13%) women demonstrated premature luteinization in two consecutive cycles. Fourteen of 52 (27%) women corrected the problem with a clomiphene citrate regimen, as compared with 32 of 38 (75%) treated with HMG and HCG; conception rates were 83 and 50%, respectively, for the patients who responded to the two regimens. Overall, regimens utilized in this study resulted in a 58% pregnancy rate in 6 months.

引用

页码：190 / 193

页数：4

共 11 条

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