CHARACTERIZATION OF Z-BLOCKED ISOMERIC DIPEPTIDES BY FAST-ATOM-BOMBARDMENT TANDEM MASS-SPECTROMETRY AND KINETIC-ENERGY RELEASE MEASUREMENTS

被引：12

作者：

MAMMOLITI, E ^{[1
]}

SINDONA, G ^{[1
]}

UCCELLA, N ^{[1
]}

机构：

[1] UNIV CALABRIA,DIPARTIMENTO CHIM,I-87030 ARCAVACATA,ITALY

来源：

ORGANIC MASS SPECTROMETRY | 1992年 / 27卷 / 04期

关键词：

D O I：

10.1002/oms.1210270422

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Fast- and slow-reacting, protonated, Z-blocked (Z = benzyloxycarbonyl) phenylalanylphenylalanine and alanylphenylalanyl diasteromeric dipeptides undergo decarboxylation through two competing pathways assisted by the migration of the urethane benzyl group either to the terminal or to the amidic nitrogens. The reaction mechanism has been proved by tandem mass spectrometric experiments. The different kinetic energy released associated with CO2 elimination allows the distinction of the S,S from the R,S isomers by mass-analysed ion kinetic-energy experiments.

引用

页码：495 / 501

页数：7

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