FABIANANE, AN UNUSUAL SECOAMORPHANE FROM FABIANA-IMBRICATA

被引：13

作者：

BROWN, GD ^{[1
]}

机构：

[1] UNIV NOTTINGHAM,DEPT CHEM,NOTTINGHAM NG7 2RD,ENGLAND

来源：

JOURNAL OF NATURAL PRODUCTS | 1994年 / 57卷 / 02期

关键词：

D O I：

10.1021/np50104a025

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A novel seco-amorphane sesquiterpene incorporating a fully saturated furo[2,3-d]1,3-dioxole system was isolated from the aerial parts of Fabiana imbricata. Such functionality is unique within the sesquiterpene family, bur does have one close relative in artemisinin (the antimalarial principle from Artemisia annual, which contains a saturated pyrano[3,2-e)1,2,4-trioxin system. The structure of fabianane [1] was elucidated by nmr spectroscopy and confirmed by comparison with nmr data for artemisinin.

引用

页码：328 / 330

页数：3