CHROMOSOMAL LOCALIZATION OF THE GENES FOR 5 ZINC-FINGER PROTEINS EXPRESSED IN MOUSE LENS

被引：7

作者：

DANCIGER, M

BRADY, J

ADAMSON, MC

FARBER, DB

PIATIGORSKY, J

KOZAK, CA

机构：

[1] LOYOLA MARYMOUNT UNIV,LOS ANGELES,CA 90045

[2] NEI,BETHESDA,MD 20892

[3] NIAID,BETHESDA,MD 20892

来源：

GENOMICS | 1995年 / 28卷 / 01期

关键词：

D O I：

10.1006/geno.1995.1103

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Based on sequence similarity to a consensus zinc finger domain, we have identified cDNAs encoding five proteins containing zinc finger nucleic acid binding motifs from a newborn mouse lens library, Utilizing these cDNAs as hybridization probes, we have mapped two of the corresponding genes to mouse Chr (chromosome) 11, two to mouse Chr 7, and one to mouse Chr 4 using two multilocus crosses, Because the zinc finger proteins encoded by these genes may be involved in regulating other genes that are expressed in lens, they can be considered candidates for the large number of yet unmapped cataract loci. (C) 1995 Academic Press, Inc.

引用

页码：39 / 43

页数：5

共 36 条

[1]

ADAMSON MC, 1991, VIROLOGY, V183, P778, DOI 10.1016/0042-6822(91)91010-E

[2] CHROMOSOMAL LOCALIZATION OF ZINC FINGER PROTEIN GENES IN MAN AND MOUSE [J].