SECONDARY ALPHA-HYDROGEN ISOTOPE EFFECTS ON THE INTERACTION OF 5-FLUORO-2'-DEOXYURIDYLATE AND 5,10-METHYLENETETRAHYDROFOLATE WITH THYMIDYLATE SYNTHETASE

被引：32

作者：

BRUICE, TW

SANTI, DV

机构：

[1] UNIV CALIF SAN FRANCISCO,DEPT BIOCHEM & BIOPHYS,SAN FRANCISCO,CA 94143

[2] UNIV CALIF SAN FRANCISCO,DEPT PHARMACEUT CHEM,SAN FRANCISCO,CA 94143

来源：

BIOCHEMISTRY | 1982年 / 21卷 / 26期

关键词：

D O I：

10.1021/bi00269a014

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

收藏

页码：6703 / 6709

页数：7

相关论文

共 36 条

[1] PURIFICATION AND PROPERTIES OF ESCHERICHIA-COLI DIHYDROFOLATE-REDUCTASE
BACCANARI, D
PHILLIPS, A
SMITH, S
SINSKI, D
BURCHALL, J
[J]. BIOCHEMISTRY, 1975, 14 (24) : 5267 - 5273
[2] MECHANISMS OF FOLATE COFACTORS
BENKOVIC, SJ
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1978, 11 (08) : 314 - 320
[3] BENKOVIC SJ, 1973, PROGR BIOORG CHEM, V2, P133
[4] BUDDENBAUM WE, 1977, ISOTOPE EFFECTS ENZY, P1
[5] Cleland W W, 1980, Methods Enzymol, V64, P104
[6] COLLINS CJ, 1970, ACS MONOGR, V167, P90
[7] 7,8-DIHYDROPTEROYL OLIGO-GAMMA-L-GLUTAMATES - SYNTHESIS AND KINETIC STUDIES WITH PURIFIED DIHYDROFOLATE-REDUCTASE FROM MAMMALIAN SOURCES
COWARD, JK
PARAMESWARAN, KN
CASHMORE, AR
BERTINO, JR
[J]. BIOCHEMISTRY, 1974, 13 (19) : 3899 - 3903
[8] CRUSBERG TC, 1970, J BIOL CHEM, V245, P5292
[9] EFFECT OF 5,10-METHYLENETETRAHYDROFOLATE ON DISSOCIATION OF 5-FLUORO-2'-DEOXYURIDYLATE FROM THYMIDYLATE SYNTHETASE - EVIDENCE FOR AN ORDERED MECHANISM
DANENBERG, PV
DANENBERG, KD
[J]. BIOCHEMISTRY, 1978, 17 (19) : 4018 - 4024
[10] THYMIDYLATE SYNTHETASE - TARGET ENZYME IN CANCER CHEMOTHERAPY
DANENBERG, PV
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1977, 473 (02) : 73 - 92

← 1 2 3 4 →