PURIFICATION OF THE 22 KDA PROTEIN SUBSTRATE OF BOTULINUM ADP-RIBOSYLTRANSFERASE C-3 FROM PORCINE BRAIN CYTOSOL AND ITS CHARACTERIZATION AS A GTP-BINDING PROTEIN HIGHLY HOMOLOGOUS TO THE RHO GENE-PRODUCT

被引：128

作者：

BRAUN, U

HABERMANN, B

JUST, I

AKTORIES, K

VANDEKERCKHOVE, J

机构：

[1] UNIV GIESSEN,RUDOLF BUCHHEIM INST PHARMAKOL,FRANKFURTER STR 107,D-6300 GIESSEN,FED REP GER

[2] LAB GENET,B-9000 GENET,BELGIUM

来源：

FEBS LETTERS | 1989年 / 243卷 / 01期

关键词：

D O I：

10.1016/0014-5793(89)81220-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：70 / 76

页数：7

共 21 条

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[2] CLOSTRIDIUM-BOTULINUM TYPE-C PRODUCES A NOVEL ADP-RIBOSYLTRANSFERASE DISTINCT FROM BOTULINUM-C2 TOXIN [J].

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[3] ADP-RIBOSYLATION OF A 21-24 KDA EUKARYOTIC PROTEIN(S) BY C-3, A NOVEL BOTULINUM ADP-RIBOSYLTRANSFERASE, IS REGULATED BY GUANINE-NUCLEOTIDE [J].

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[4] BOTULINUM ADP-RIBOSYLTRANSFERASE C-3 - PURIFICATION OF THE ENZYME AND CHARACTERIZATION OF THE ADP-RIBOSYLATION REACTION IN PLATELET MEMBRANES [J].

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[5] ADP-RIBOSYLATION OF PLATELET ACTIN BY BOTULINUM C2-TOXIN [J].

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[6] EPINEPHRINE INHIBITS ADENYLATE-CYCLASE AND STIMULATES A GTPASE IN HUMAN-PLATELET MEMBRANES VIA ALPHA-ADRENOCEPTORS [J].

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[7] BOTULINUM-C2 TOXIN ADP-RIBOSYLATES ACTIN [J].

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[8] ALTERATIONS IN THE PHENOTYPE OF PLANT-CELLS STUDIED BY NH2-TERMINAL AMINO-ACID-SEQUENCE ANALYSIS OF PROTEINS ELECTROBLOTTED FROM TWO-DIMENSIONAL GEL-SEPARATED TOTAL EXTRACTS [J].

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[9]

BAUW G, 1988, J PROTEIN CHEM, V7, P194

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BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

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