USE OF SODIUM AUROTHIOMALATE DURING LACTATION

被引：8

作者：

BENNETT, PN

HUMPHRIES, SJ

OSBORNE, JP

CLARKE, AK

TAYLOR, A

机构：

[1] UNIV SURREY,ROBENS INST IND & ENVIRONM HLTH SAFETY,GUILDFORD GU2 5XH,SURREY,ENGLAND

[2] ROYAL UNITED HOSP,DEPT PAEDIAT,BATH,AVON,ENGLAND

来源：

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 1990年 / 29卷 / 06期

关键词：

D O I：

10.1111/j.1365-2125.1990.tb03703.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The report concerns a mother who breast fed her infant whilst receiving sodium aurothiomalate for the treatment of rheumatoid arthritis. The milk:serum concentration ratio was not constant, reflecting the non‐ concurrence of the concentration‐time profiles of gold in milk and maternal serum after i.m. injection. Gold was detected in the infant's serum. Calculations indicate that the weight‐adjusted dose to the infant exceeded that received by the mother. 1990 The British Pharmacological Society

引用

页码：777 / 779

页数：3

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