LIPIODOL RETENTION AND MASSIVE NECROSIS AFTER LIPIODOL-CHEMOEMBOLIZATION OF HEPATOCELLULAR-CARCINOMA - CORRELATION BETWEEN COMPUTED-TOMOGRAPHY AND HISTOPATHOLOGY

被引：60

作者：

IMAEDA, T

YAMAWAKI, Y

SEKI, M

GOTO, H

IINUMA, G

KANEMATSU, M

MOCHIZUKI, R

DOI, H

SAJI, S

SHIMOKAWA, K

机构：

[1] Department of Radiology, Gifu University School of Medicine, Gifu City, 500

[2] Department of Second Surgery, Gifu University School of Medicine, Gifu City, 500

[3] Department of Laboratory Medicine, Gifu University School of Medicine, Gifu City, 500

来源：

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY | 1993年 / 16卷 / 04期

关键词：

LIPIODOL-CHEMOEMBOLIZATION; HEPATOCELLULAR CARCINOMA; LIPIODOL RETENTION; MASSIVE NECROSIS; CT;

D O I：

10.1007/BF02602962

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This retrospective study examined the computed tomography (CT) criteria for judging the effectiveness of transcatheter arterial Lipiodol-chemoembolization (Lp-chemo-TAE) in 35 cases with hepatocellular carcinoma (HCC). Massive necrosis, defined as involving 97% or more of the HCC nodule, was observed in 15 cases after Lp-chemo-TAE, whereas nonmassive necrosis, defined as involving less-than-or-equal-to 96% of the HCC nodule, was observed in the remaining 20 cases. In 12 of 15 cases (80%) with massive necrosis, uniform dense retention of Lipiodol (Lp) was observed throughout the HCC nodule on CT images 3-4 weeks after Lp-chemo-TAE as opposed to only one (5%) of 20 cases with nonmassive necrosis (p < 0.01). Eight of nine cases (89%) with massive necrosis had tumor attentuation values of 365 Hounsfield units (HU) or greater on CT images 3-4 weeks after embolization, as opposed to only four (27%) of 15 cases with nonmassive necrosis (p < 0.01). We conclude that the effectiveness of the Lp-chemo-TAE can be judged on CT from the degree and duration of Lp retention in the HCC nodule and the measurement of the attenuation value of the HCC nodule.

引用

页码：209 / 213

页数：5

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