EFFECTS OF MACROPHAGE COLONY-STIMULATING FACTOR ON REDUCTION OF VIABLE BACTERIA AND SURVIVAL OF MICE DURING LISTERIA-MONOCYTOGENES INFECTION - CHARACTERISTICS OF MONOCYTE SUBPOPULATIONS

被引：21

作者：

KAYASHIMA, S

TSURU, S

SHINOMIYA, N

KATSURA, Y

MOTOYOSHI, K

ROKUTANDA, M

NAGATA, N

机构：

[1] NATL DEF MED COLL,DEPT MICROBIOL,TOKOROZAWA,SAITAMA 359,JAPAN

[2] NATL DEF MED COLL,DEPT INTERNAL MED 3,TOKOROZAWA,SAITAMA 359,JAPAN

来源：

INFECTION AND IMMUNITY | 1991年 / 59卷 / 12期

关键词：

D O I：

10.1128/IAI.59.12.4677-4680.1991

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Mice could well tolerate infection with a lethal dose of Listeria monocytogenes after intraperitoneal preinjections with 250-mu-g of macrophage colony-stimulating factor (M-CSF) per kg of body weight for 5 days. The characteristic changes in the surface markers (Mac-1, LFA-1, and F4/80) of peripheral monocytes were also investigated in order to analyze the mechanism of protection by M-CSF. This investigation shows the excellent effect of intraperitoneal preinjections of M-CSF on the reduction of viable Listeria organisms and the improvement of survival after an intravenous Listeria infection.

引用

页码：4677 / 4680

页数：4

共 21 条

[1] STIMULATORY EFFECTS OF PURIFIED MACROPHAGE COLONY-STIMULATING FACTOR ON MURINE RESIDENT PERITONEAL-MACROPHAGES [J].

AMPEL, NM ;

WING, EJ ;

WAHEED, A ;

SHADDUCK, RK .

CELLULAR IMMUNOLOGY, 1986, 97 (02) :344-356

[2]

BURGESS AW, 1985, J BIOL CHEM, V260, P6004

[3] PRODUCTION OF COLONY-STIMULATING FACTORS (CSFS) DURING INFECTION - SEPARATE DETERMINATIONS OF MACROPHAGE-CSF, GRANULOCYTE-CSF, GRANULOCYTE-MACROPHAGE-CSF, AND MULTI-CSF [J].

CHEERS, C ;

HAIGH, AM ;

KELSO, A ;

METCALF, D ;

STANLEY, ER ;

YOUNG, AM .

INFECTION AND IMMUNITY, 1988, 56 (01) :247-251

[4]

CZUPRYNSKI CJ, 1984, J LEUKOCYTE BIOL, V35, P193

[5] PURIFICATION OF HUMAN URINARY COLONY-STIMULATING FACTOR BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

HATAKE, K ;

MOTOYOSHI, K ;

ISHIZAKA, Y ;

SATO, M ;

TAKAKU, F ;

MIURA, Y .

JOURNAL OF CHROMATOGRAPHY, 1985, 344 (NOV) :339-344

[6] EFFECT OF MACROPHAGE COLONY-STIMULATING FACTOR ON THE FUNCTION OF RESIDENT PERITONEAL-MACROPHAGES [J].

KANADA, T ;

SHIKITA, M ;

TSUNEOKA, K ;

SAKAI, N ;

TOMITA, T ;

KANEGASAKI, S .

JOURNAL OF PHARMACOBIO-DYNAMICS, 1987, 10 (05) :215-219

[7]

MAGEE DM, 1987, IMMUNOLOGY, V62, P373

[8]

METCALF D, 1986, BLOOD, V67, P257

[9]

NEWBORG MF, 1980, J IMMUNOL, V124, P571

[10]

NORTH RJ, 1974, MECHANISMS CELL MEDI, P185

← 1 2 3 →