CONDITIONING REGIMENS FOR ALLOGENEIC BONE-MARROW TRANSPLANTATION

被引：23

作者：

COPELAN, EA

机构：

[1] OHIO STATE UNIV, INTERNAL MED, COLUMBUS, OH 43210 USA

[2] OHIO STATE UNIV, ARTHUR G JAMES CANC HOSP & RES INST, COLUMBUS, OH 43210 USA

来源：

BLOOD REVIEWS | 1992年 / 6卷 / 04期

关键词：

D O I：

10.1016/0268-960X(92)90019-M

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Conditioning regimens for transplantation are important in determining transplant outcome. This review focuses on transplantation in aplastic anemia and leukemia using marrow from HLA-identical siblings. Results of conditioning with newer regimens such as busulfan plus cyclophosphamide and etoposide plus total body irradiation are reviewed and compared to results achieved with cyclophosphamide and total body irradiation. The potential for improved results using recent innovations such as dose adjustment of busulfan, agents which may decrease transplant-related toxicity, and directed radiation are discussed.

引用

页码：234 / 242

页数：9

共 87 条

[1]

BARRETT AJ, 1989, BLOOD, V74, P862

[2] REGIMEN-RELATED TOXICITY IN PATIENTS UNDERGOING BONE-MARROW TRANSPLANTATION [J].

BEARMAN, SI ;

APPELBAUM, FR ;

BUCKNER, CD ;

PETERSEN, FB ;

FISHER, LD ;

CLIFT, RA ;

THOMAS, ED .

JOURNAL OF CLINICAL ONCOLOGY, 1988, 6 (10) :1562-1568

[3]

BENSINGER WI, 1990, BLOOD, V76, pA527

[4]

BIANCO JA, 1991, BLOOD, V78, P1205

[5]

BIANCO JA, 1991, BLOOD, V78, pA237

[6]

BIGGS JC, IN PRESS BLOOD

[7]

BLAISE D, 1992, REPORT GROUPE ETUDES, V79, P2578

[8]

BLUME KG, 1987, BLOOD, V69, P1015

[9]

BOSTROM B, 1990, BONE MARROW TRANSPL, V5, P83

[10]

BUCKNER CD, 1975, EXP HEMATOL, V3, P275

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